France Projects Houses Area: 260 m² Year Completion year of this architecture project CopyHouses•Lyon, France Save this picture!+ 11 Share Architects: AUM Pierre Minassian Area Area of this architecture project ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/11478/biscuit-house-aum Clipboard Manufacturers Brands with products used in this architecture project Manufacturers: Glas TröschText description provided by the architects. The house is located in a small village in the area of Lyon on a very steep slope and facing an open landscape. It is situated on the fringe of a natural reservation where no house can be built.The building of the house was very complex for various reasons:- it was very difficult to get the authorization to build contemporary architecture on that location.Save this picture!Recommended ProductsEnclosures / Double Skin FacadesRodecaRound Facade at Omnisport Arena ApeldoornDoorsRabel Aluminium SystemsMinimal Sliding Door – Rabel 62 Slim Super ThermalWoodSculptformTimber Click-on BattensWindowsJansenWindows – Janisol Primo- building was difficult also because there was no way to access the lower part of the building site so that it was necessary to find a compromise with the neighbour for him to allow the building of a path going along his own terrain.- I made the external wood curtain myself which required more than 200 hours of work.The house is a 23m x 7m parallelepiped, made of concrete, steel and glass, embedded in the slope of the terrain.It is composed of two floors which both have direct access to the garden.The structure is made both in concrete and steel. All the materials are natural and untreated for them to keep their original aspect. Concrete is used for the envelope and the floors; steel is used for the pillars and for the window frames ; and untreated exotic wood (iroko) is used for the external curtain.Save this picture!All the rooms are exposed to daylight. A large opening in the floor of the first storey enables daylight to reach the groundfloor.The wood curtain is the specificity of the house. It is composed of shapes that have been named ‘biscuits’ by the first French magazine who published the house. I found the name was appropriate and I decided to keep it.- it helps the house integrate in the landscape where local houses are built in beige stone. From a distance the curtain reminds, in a contemporary way, of the traditional assembly of stones.- it also has a thermal role as it reduces the impact of the sun in the bedrooms in the morning. This is important as those rooms face the East and have windows covering the whole façade.- it finally enables to visually insulate the bedrooms from the outside as by creating a mirror effect between the curtain and the window pane.Save this picture!The bedrooms are upstairs and the ‘day’ rooms are downstairs. The groundfloor is lined with windows going from floor to ceiling in order to enjoy the landscape all day long.In the living-room huge French windows (8m x 3m) open on the garden so that you have the feeling that the garden is part of the house; there is a sensation of continuity between inside and outsideWithin the house there is also a sensation of uninterrupted continuity as the heaviest and most cumbersome elements (the fireplace and the stairway) are suspended over the floor.The fireplace, both cumbersome and light, acts as a separation between the living-room and the music-room. It is made in steel and is partially filled with refractory concrete providing thermal inertia and heating comfort.The suspended stairway was built without risers for maximum daylight to go through and not to block the view.Project gallerySee allShow lessORDOS 100 #9: Sou FujimotoArticlesRefuge Pavilion / Francisco Portugal e GomesSelected Projects Share Biscuit House / AUM Pierre MinassianSave this projectSaveBiscuit House / AUM Pierre Minassian ArchDaily Biscuit House / AUM Pierre Minassian Year: 2008 “COPY” ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/11478/biscuit-house-aum Clipboard “COPY” CopyAbout this officeAUM Pierre MinassianOfficeFollowProductsWoodGlassConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesLyonHousesWoodFrancePublished on January 12, 2009Cite: “Biscuit House / AUM Pierre Minassian” 12 Jan 2009. ArchDaily. Accessed 12 Jun 2021.
SHARE By Hoosier Ag Today – Jul 22, 2018 SHARE PETA Reaches ‘a New Low’ Trying to Capitalize on Trade War with China People for the Ethical Treatment of Animals is placing a new billboard in Des Moines, Iowa, encouraging people to eat tofu. They say soybean farmers want people to go vegan and support the growers through a trade dispute with China. However, the Iowa Soybean Growers Association is quick to point out that it isn’t asking consumers to give up meat. An Iowa Soybean Association spokesman says the billboard is “misleading and disingenuous,” and that “PETA doesn’t speak for Iowa or U.S. soybean growers.” PETA’s new billboard will say “America’s Soybean Farmers Want You… to go Vegan! Tofu: Born in China but raised in the USA.”The group chose Des Moines because Iowa is the nation’s second-largest soybean grower. “It’s our civic duty, in the face of a trade war, to choose healthy, tasty, and downright patriotic dishes like veggie burgers and soy-based hot dogs,” says PETA president Ingrid Newkirk. However, the Iowa Soybean Association says capitalizing on a trade dispute to further its anti-meat agenda is in poor taste, calling it “a new low for PETA.”Source: NAFB News Service Facebook Twitter Previous articleHabitat for Humanity Ag Build at the State FairNext articleNavarro Discounts Trade War Impact on Ag Hoosier Ag Today Facebook Twitter Home Indiana Agriculture News PETA Reaches ‘a New Low’ Trying to Capitalize on Trade War with…
Twitter + posts Twitter Another series win lands TCU Baseball in the top 5, earns Sikes conference award Run. Rest. Religion. Repeat.Derrick Mokaleng has instilled this routine into his everyday life and it shows when he’s on the track.Mokaleng, a sophomore entrepreneurial management major, has broken countless NCAA records while running at TCU. Mokaleng recorded the second fastest 600-yard run in collegiate history Jan. 19, at the Red Raider Invitational in Lubbock, Texas.Mokaleng finished in second place and recorded a time of 1:08, just 0.02 seconds behind Vincent Crisp, the Texas Tech runner who set the collegiate 600 record.“Honestly with that race, I just went there to run the race,” Mokaleng said. “I wasn’t thinking of running a good time because I wasn’t feeling good going into the race. Then on the last lap, I just decided to stick with the guy from Texas Tech and then we just pushed each other to the line. We found out later that we ran the two fastest times in college history,” he said with a casual shoulder shrug.”Coming to the United States from South Africa, Mokaleng had to adjust to the differences. He says the track structures, weather conditions, coaching and workouts are all different than back home.“At home, I focused more on endurance and coming here now I focus more on speed and strength,” he said.Mokaleng also holds the fastest 400-meter time in NCAA Division 1 after recording a 45.17 at the Sun Angel Classic in Tempe, Arizona, on April 8, 2018.Derrick MokalengVenngage InfographicsDirector of Track and Field Darryl Anderson said Mokaleng’s passion is transparent in practices.“His work ethic and his commitment to the sport are what make him so special,” he said. “If you take your three to four hour practice days, student-athletes have another 20 hours to themselves.”Anderson said it’s what athletes do with the remainder of their day that dictates their success.“I have a calendar on my wall where I mark down all my times that I want to achieve each year,” Mokaleng said. “Every time I reach those goals or times I’m just happy with my progress and the work I’ve put in.”Mokaleng said he discovered his passion for running at seven years old when his dad got him and his two siblings interested in the sport.“My life has always revolved around running,” Mokaleng said. “That’s all I knew in high school, all I did was run.”He said when he was younger he wasn’t always the most talented of athletes, but he credits his recent success to God.“I was always small and I wasn’t the strongest athlete,” Mokaleng said. “I think that my strength and all the things I am able to accomplish on the track is because of God and his grace. It’s a blessing from God just the talent that I have today so I just give it all to Him.”With two more years left at TCU, Coach Anderson said he hopes Mokaleng continues to grow as a person and athlete.“He’s becoming a man– he’s away from home, he doesn’t have parents here to give him the guidance,” he said. “I give him as much guidance as I can on and off the track but I also have to allow him to grow. But at the end of the day, my goal for him is to get his college education and his degree.”Although Mokaleng is in Fort Worth for 10 months of the year, he still finds ways to represent his country on the track.Anderson said Mokaleng ran on the South African junior team and is hoping to represent South African in the World Championships next year.“Every time I put on the green and gold of South Africa I feel proud because I know I’m not just representing myself and my family,” Mokaleng said. “I’m also representing the country, the people of South Africa. Just being able to represent TCU and my country is one of my proudest moment I can think of.”At the 2018 TCU All-Sports Banquet, Mokaleng was awarded the Male Breakout Athlete of the Year. Previous articleHonor students help revive English as a second language course for employeesNext articleTwo brothers strengthen relationship through music Alexis Guerrero RELATED ARTICLESMORE FROM AUTHOR Alexis Guerrero Dean of Admission reflects on university’s growing recognition TCU rowing program strengthens after facing COVID-19 setbacks Alexis Guerrerohttps://www.tcu360.com/author/alexis-guerrero/ Where to watch Super Bowl LIII in Fort Worth Alexis Guerrerohttps://www.tcu360.com/author/alexis-guerrero/ Linkedin Alexis Guerrerohttps://www.tcu360.com/author/alexis-guerrero/ Facebook Alexis Guerrerohttps://www.tcu360.com/author/alexis-guerrero/ Linkedin Facebook ReddIt Alexis Guerrero is a junior sports broadcasting and journalism double major from Fort Worth, Texas. She is a dog, baseball, and pizza enthusiast. print ReddIt Hector Gutierrez’s worldly experience has helped establish Beach Volleyball Baseball adjusts to losing numerous key players from previous seasons TCU baseball finds their biggest fan just by saying hello
In order to measure ice deformation at frequent intervals across the Brunt Ice Shelf, Antarctica, 64 markers were planted to form a network of overlapping braced quadrilaterals. This network was triangulated in 1966 and, after a 10-month interval, again in 1967. Throughout the periods of observation the survey figures suffered continual distortion, and any computation method must allow for this. Making the assumption that ice movement at each marker is linear it is possible to interpolate the positions of observed stations and to process the triangulation scheme as a series of resections. To solve these a computer-oriented resection solution was developed, and adapted to accept measured lengths in addition to angles as input data. In order to correct for Earth-curvature, and to utilise observed true azimuths, a simple spheroid model was adopted. The survey yielded positions of all markers at the times of occupation; position accuracy relative to the origin of the scheme was 1 : 40,000. Values of ice velocity deduced from these positions ranged from 50 metres per year on the grounded inland ice sheet to 350m yr−1 at the front of the floating ice shelf.
A new aspidostomatid bryozoan from the Cape Melville Formation (Lower Miocene) of King George Island, West Antarctica
Fragments of large, bilamellar aspidostomatid bryozoan colonies occur in Early Miocene glaciomarine sedimentary sequences of the Cape Melville Formation, King George Island, South Shetland Islands, West Antarctica. Investigation of the morphological characters of this aspidostomatid cheilostome shows that it represents a new species, which is described herein as Aspidostoma melvillensis sp. n. A combination of the colony-growth pattern, inferred co-occurring biota and associated sedimentary structures indicates a comparatively deep-water, outer shelf palaeoenvironmental setting. This Miocene occurrence of Aspidostoma melvillensis sp.n. emphasizes a biogeographical link with adjacent Southern Hemisphere regions during the early Neogene.
Tags: BYU Men’s Basketball/Utah Men’s Basketball FacebookTwitterLinkedInEmailSALT LAKE CITY-Friday, BYU and the University of Utah agreed to a 4-game series in men’s basketball which will start this upcoming season. This series was confirmed by a University of Utah spokesperson.This game is slated for December 12, 2020 at the Marriott Center in Provo.This is the second series between the two programs since the cancellation of the 2016 rivalry game.Utah will host the Cougars in 2021 and 2023 with the 2022 game slated for Provo.This will be the 261st all-time meeting between these two bitter rivals with the Cougars leading the Utes 131-129 all-time.Since the Utes joined the PAC-12 in 2011, the squads have met eight times on the hardwood. BYU and Utah have each won 4 times in that span.The Cougars are losing five scholarship players to graduation from last year’s squad. The Utes are returning the majority of their young core as head coach Larry Krystkowiak had no scholarship players that were seniors last season. Brad James April 10, 2020 /Sports News – Local BYU/Utah Men’s Basketball Agree To A New 4-Game Series To Start in 2020 Written by
Improved availability, product quality and good customer service have all led to a huge sales increase at Sainsbury’s in-store bakery in Lincoln.Turnover is up from £5,000 a week – when bakery manager Nick Markiewicz took over seven years ago – to £13,000, which wowed the judges at Sainsbury’s National Retail Awards. Markiewicz and his colleagues beat more than 450 other Sainsbury’s stores to win Bakery Team of the Year.Markiewicz said: “We are taking £27,000 a week and sales have been in double-digit growth for six years on the trot. Availability is key for me and our aim is to have our shelves looking as strong at 8pm as they do first thing in the morning.”He said the team put very small batches through on daily lines to avoid wastage and that shoppers had responded well to improvements. “We’re picking up new customers as well as keeping the old ones.”Now in their second year, the chain’s National Retail Awards were set up by Sainsbury’s to recognise outstanding performance across its stores.
Milling about the “Great Court” at Eliot House, students greeted old friends from last semester and new sophomores with enthusiasm. Games such as Frisbee broke out, and a few brave souls, including sophomore Kris Liu and junior Leah Reis-Dennis, sang or performed for their housemates.
It has long been known that cancer cells use nutrients differently than normal cells. In recent years, the rapidly re-emerging field of cancer metabolism has shed new light on the ways that cancers use glucose to grow and thrive, demonstrating that manipulation of an enzyme called PKM2 is important to this metabolic process.Now a new study led by a scientific team at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS) has uncovered another key mechanism that cancer cells use as part of their survival strategy — and once again it seems that they are using PKM2 to their advantage.Reported in the Nov. 3 express online edition of Science, the new findings show that by keeping PKM2 activity at lower-than-normal levels, cancer cells are able to withstand damage caused by oxidative stress and the generation of potentially toxic reactive oxygen species (ROS). Importantly, the study shows that small-molecule PKM2 activator drugs could be a way to interfere with this process — and thereby disrupt tumor growth.“Many cancer cells take up glucose at higher rates than most normal cells, and then use the sugar in a distinct way to fuel their proliferation,” explains senior author Lewis Cantley, director of the Cancer Center at BIDMC and the William Bosworth Castle Professor of Medicine at HMS. “Several years ago, it was discovered that the M2 form of the pyruvate kinase enzyme [PKM2] plays a key role in this metabolic process. Now, these new findings demonstrate yet another way that cancer cells are able to manipulate PKM2 to their advantage, suggesting that by keeping PKM2 activity low, cancer cells channel incoming glucose to metabolic pathways that generate antioxidants, and thereby survive oxidative stress.”Glycolysis is a multistep process in which glucose is broken down so that cells can make use of the sugar for energy and other essential functions, and the PKM2 enzyme is responsible for the final step of the process. Previous work from the Cantley lab had suggested that inhibition of PKM2 by growth-factor signaling was providing a stall-point in the glycolytic process, functioning like a dam in a river to enable glucose breakdown products to accumulate and eventually spur cancer cell growth.But the investigators thought there might be more to the story.“Growth-factor signaling emerged relatively late in evolution but glycolysis is a highly conserved process and occurs in bacteria much like it occurs in human cells,” says Dimitrios Anastasiou, a research fellow in the Department of Signal Transduction at BIDMC and the Department of Systems Biology at HMS and first author of this new paper. “We were intrigued by the possibility that something other than growth factors might also be influencing the activity of PKM2.”They turned their attention to reactive oxygen species (ROS), chemically reactive molecules that form as a natural byproduct of cell metabolism and can lead to cell damage when not kept under control. “To survive, cancer cells require the ability to squelch potentially toxic ROS molecules, which can arise as a result of both their aberrant metabolism as well as their environment,” explains Anastasiou. “We thought that PKM2 might somehow be playing a supporting role in tamping down ROS.”To test this hypothesis, the scientific team embarked on a series of experiments that showed ROS can inhibit PKM2 activity, and that low PKM2 activity under oxidative stress helps push glucose into pathways that generate antioxidant molecules.“We engineered cells to express a PKM2 mutant that is resistant to ROS-induced inhibition,” says Anastasiou. “This showed us that when challenged by oxidative stress these cells died more readily than cells expressing the wild-type oxidizable version of PKM2. Strikingly, we also observed that oxidation-resistant PKM2 could not efficiently support the ability of human lung-cancer cells to form tumors in mice, but that this defect could be rescued by treating mice with an antioxidant in their water.”The team also collaborated with the National Institutes of Health (NIH) Chemical Genomics Center to identify small-molecule PKM2 activators, drugs that keep PKM2 active and thereby prevent cancer cells from using glucose to grow and survive. Treatment of cancer cells with these activators kept PKM2 activity at high levels even under oxidative stress. It also sensitized cells to oxidant-induced death similar to the oxidation-resistant mutant.“This paper demonstrates that oxidants inhibit PKM2 activity,” says Cantley. “While moderate ROS levels can influence growth signaling and promote proliferation, too much ROS can cause irreversible damage to cells, and lead to their demise. We propose that expression of PKM2 allows cancer cells greater flexibility in manipulating how glucose is metabolized to ensure that ROS concentrations remain low.“Now that we’ve figured out yet another scheme that cancer uses to survive, we might be able to use small-molecule PKM2 activators to prevent cancer from inhibiting the enzyme,” he adds. “Because radiation therapy and some chemotherapeutic agents are believed to kill cancer cells by inducing excess ROS, there is a possibility that PKM2 activators may improve the efficiency of these therapies.”This work was supported by grants from the National Institutes of Health, the Starr Cancer Consortium, the Molecular Libraries Program of the National Institutes of Health Roadmap for Medical Research, and the Intramural Research Program of the National Human Genome Research Institute at the National Institutes of Health.
CUNA’s proposed new membership bylaws removed language that required member credit unions to also maintain league membership. It also removed language that automatically made credit unions members of CUNA when they joined a league.Three documents – the proposed restated bylaws, a comparison of the current and proposed bylaws and the current bylaws – were emailed to leagues and CUNA members Monday. continue reading » 1SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr