WASHINGTON – For the first time in 30 years, the U.S. Marine Corps will air an ad during the Super Bowl, using an online-only spot Sunday to target a young, tough, tech-savvy audience for potential recruits looking for a challenge.The high-powered, battle-heavy, 30-second ad shows Marines deploying from ships in amphibious vehicles, dropping bombs from aircraft and hurling a shoulder-launched drone into the air.“It’s not just the ships, the armour or the aircraft. It’s something more. It’s the will to fight and determination to win found inside each and every Marine that answers a nation’s call,” the announcer says, as the camera follows a squad of Marines storming off helicopters into a mock firefight while explosions erupt around them.The goal, said Maj. Gen. Paul Kennedy, head of the Marine Corps Recruiting Command, is to reach young men and women who have faced and conquered challenges in their life, probably played physical sports such as wrestling or rugby, and have a bit of that fighting spirit.Network television viewers of the game won’t see the Marine spot. But those watching through online streaming services — which charge a fraction of the advertising price — will see it twice.“I’m not trying to enlist fathers or mothers, I’m trying to enlist 18- to 24-year-olds,” said Kennedy. “And they tend to be cord cutters. They take in entertainment differently and they tend to do it on a device rather than a television.”The Marine Corps would not provide the exact cost because the specific pricing is proprietary. But the online ad represents a savings of nearly 85 per cent over the broadcast price. Thirty-second slots are going for more than $5 million for broadcast airtime alone. And the online ad — which can be viewed on www.marines.com — is expected to reach more than 20 million viewers.As the military services struggle to meet recruitment goals in these times of low unemployment, they are competing for many of the same young people — physically fit high school graduates who can score 50 or higher on the military’s aptitude test.The Marine Corps is on target to meet its recruitment goal of about 38,000 for the budget year ending Sept. 30. But recruiters have historically found that the months of February through May are the toughest for finding new enlistments. By this time, many high school seniors have decided what they will do or what college they will attend.So Kennedy is hoping the ad will reach some who may still be open to serving in the Marine Corps. Targeting the streaming broadcast has now become a more effective option as viewership online grows, he said, and is the best way to reach more young people while spending less money.“I don’t have unlimited funds,” he said. “And this is probably the most-watched event, as we move into the toughest months of recruiting.”The visuals in the ad, he said, go to the heart of what Marines do, deliberately focusing on the fight rather than some of the intangibles such as the potential for paid college tuition, bonuses or other incentives. The images are designed to attract people who are tough and resilient — key words the Marines use repeatedly to describe the force.The battle scenes were filmed on the West Coast with Marines participating in a military exercise called Dawn Blitz in order to show more realistic scenarios. The ad also shows Marines deployed on the USS Essex, an amphibious assault ship, which was off the California coast for training, to mimic a deployment near the shores of an adversary.“This ad talks to the fighting spirit of young people that have come up through high school,” Kennedy said. “We want young, tough, smart warriors that want to continue to seek challenges, and we’re seeking them from men and women from all walks of life.”
Washington DC: A steady supply of beer may have helped keep the Wari empire in Peru running for 500 years, eventually giving rise to the Incas, a study has found. At its height, the Wari empire covered an area the size of the Eastern seaboard of the US from New York City to Jacksonville. It lasted from 600 to 1100 AD, before eventually giving rise to the Inca. Archaeologists are studying remnants of the Wari culture to see what kept it ticking. Also Read – Saudi Crown Prince ‘snubbed’ Pak PM, recalled jet from US”This study helps us understand how beer fed the creation of complex political organisations,” said Ryan Williams, an associate curator at the Field Museum in the US. “We were able to apply new technologies to capture information about how ancient beer was produced and what it meant to societies in the past,” said Williams, lead author of the study published in the journal Sustainability. Nearly twenty years ago, the team discovered an ancient Wari brewery in Cerro Baul in the mountains of southern Peru. Also Read – Record number of 35 candidates in fray for SL Presidential polls”It was like a microbrewery in some respects. It was a production house, but the brewhouses and taverns would have been right next door,” said Williams. Since the beer they brewed, a light, sour beverage called chicha, was only good for about a week after being made, it was not shipped offsite — people had to come to festivals at Cerro Baul to drink it. These festivals were important to Wari society — between one and two hundred local political elites would attend, and they would drink chicha from three-foot-tall ceramic vessels decorated to look like Wari gods and leaders. “People would have come into this site, in these festive moments, in order to recreate and reaffirm their affiliation with these Wari lords and maybe bring tribute and pledge loyalty to the Wari state,” Williams said in a statement. In short, beer helped keep the empire together, researchers said. To learn more about the beer that played such an important role in Wari society, researchers analysed pieces of ceramic beer vessels from Cerro Baul. They used several techniques, including one that involved shooting a laser at a shard of a beer vessel to remove a tiny bit of material, and then heating that dust to the temperature of the surface of the Sun to break down the molecules that make it up. From there, the researchers were able to tell what atomic elements make up the sample, and how many — information that told researchers exactly where the clay came from and what the beer was made of. To check that the ingredients in chicha could indeed be transferred to the brewing vessels, the researchers worked with Peruvian brewers to recreate the brewing process.
ANCHORAGE, Alaska — A man rescued from a drifting sheet of floating ice in northwest Alaska says he had to jump from floe to floe as the ice started breaking into smaller pieces.The Anchorage Daily News reports Phillip Rode, John Culp Jr. and James Gibson were rescued by a helicopter Sunday after they became stranded miles off the coast of Nome.Rode says the group was recovering gold mining equipment from an ice shelf that was beginning to detach from a beach.The ice broke loose as they were moving equipment, but they didn’t immediately realize they had drifted into the Bering Sea.Rode says the ice started cracking under them, and the floes became farther apart.He says he ended up on an ice floe no bigger than a Volkswagen Beetle.___Information from: Anchorage Daily News, http://www.adn.comThe Associated Press
From April 7-28 there is a water drinking challenge happening called Water You Drinking? This challenge is being launched on World Health Day with the goal of increasing awareness about the rise of diabetes and the risk factors associated with the disease. Although there are many factors involved in the care and management of diabetes, one vital component is lifestyle and diet. The goal of this challenge is to increase daily water intake, or replace your daily liquid intake made up of sugary, high calorie and high caffeine beverages, with water. The Canadian Diabetes Association provides resources for those interested in learning more about the importance of maintaining a healthy lifestyle, which includes diet. Many people’s daily liquid intake is made up of high calorie and sugary beverages such as juice, pop, energy drinks, coffee, lattes, etc. Brock University’s Health Management department is challenging individuals to switch out those sugary beverages for water during this three-week challenge. In addition to the numerous benefits that hydrating with water provides for our bodies, increasing your daily water intake also helps you live a healthier lifestyle by decreasing the intake of those sugary beverages. Sugary beverages cause your blood-sugar level to rise, which over time has proven to have adverse health effects. The goal is to drink eight 8-oz glasses of water per day. Health Management will provide the first 200 registrants with a water bottle from Wellness Day 2015. Prior to the launch of the challenge, those registered will receive an email with an attachment to the Water You Drinking? Challenge Tracking Form. Staff and faculty are asked to register on Focus on Learning. Health Management will draw two prizes for campus store gift cards at the end of the challenge, one for those who met the goal of consuming eight glasses of water daily throughout the challenge and a second draw including all participants of the challenge.For more information about diabetes click here.
The most recent addition to Epiroc’s Minetruck series has been engineered for smart and efficient haulage. The rugged Minetruck MT54 is a powerhouse just like the larger Minetruck MT65. The more compact Minetruck MT54 is designed for 54 t load capacity and higher ramp speeds than its predecessor Minetruck MT5020.“Minetruck MT54 is based on the very successful Minetruck MT65, so experience and reliability are built-in from the beginning.” says Marcus Lundbergh, Global Product Manager Haulage Trucks at Epiroc.Minetruck MT54 also features Epiroc’s proprietary Rig Control System (RCS), it is ready for automation and can be equipped with Certiq for added intelligence. The optional telematics system solution gathers and compiles data to help optimise operations and plan maintenance. “With its built-in smartness, this haulage truck is prepared for the future,” affirms Lundbergh.
Wednesday night was perfect time for the favorites at DKB Bundesliga. Rhein Neckar Lowen scored 44 goals in away match against Emsdetten, while Flensburg beat Bergischer with +19 with fantastic defense which received only 15 goals. THW Kie had easy job against Goppingen, while the most intestering clashes have been seen in Eisenach and Lemgo…RESULTS:ThSV Eisenach 27:28 (14:11) HSG Wetzlar 6.MT Melsungen32:22+25 Rhein Neckar LowenTHW Kiel 12.FRISCH AUF! Göppingen21:35-15 18.TV Emsdetten7:49-177 TBV Lemgo 29:27 (19:13) TSV Hannover-BurgdorfSTANDINGS: SG Flensburg-H. 34:15 (17:8) Bergischer HC 11.HSG Wetzlar23:29-20 16.HBW Balingen-Weilstetten14:40-71 10.TBV Lemgo25:31-30 1.THW Kiel49:7+164 15.Bergischer HC17:39-76 4.HSV Handball42:10+82 THW Kiel 31:20 (17:8) Frisch Auf Göppingen ← Previous Story Norway qualifies for Women’s EHF EURO 2014! Next Story → DANISH FEMALE BEST 7: Mette Gravholt the No.1 3.SG Flensburg-Handewitt46:10+154 17.ThSV Eisenach11:43-130 8.TuS N-Lübbecke27:27-28 5.Füchse Berlin38:16+79 14.VfL Gummersbach18:34-64 13.TSV GWD Minden18:34-52 2.Rhein-Neckar Löwen47:9+181 9.TSV Hannover-Burgdorf26:30-47 TV Emsdetten 32:44 (12:19) Rhein-Neckar Löwen 7.SC Magdeburg29:25+25
Japon : l’éruption du Mont Shinmoedake menace les habitationsEntré en éruption mercredi dernier, le volcan Shinmoedake crache des cendres et des roches. Son activité est telle qu’un millier de personnes ont dû quitter leurs habitations dans le sud-ouest du Japon.Cela fait 300 ans que le Mont Shinmoedake n’avait pas été aussi actif. Situé sur l’île japonaise de Kyushu entre Kagoshima et Miyazaki, son activité a recouvert de cendres les cultures maraîchères des environs et perturbe le trafic aérien, rapporte le NouvelObs.com. À lire aussiLe Kilimandjaro, un volcan dormant caché dans la plus haute montagne d’AfriqueEnviron 600 résidents de la localité de Takaharu, qui se situe au pied de la montagne de 1.421 mètres, ont accepté de laisser leurs maisons dimanche pour rejoindre des gymnases et autres centres. Le volcan continuait hier de cracher une épaisse colonne de fumée et de cendres à plusieurs milliers de mètres dans le ciel.Dans un communiqué, l’Agence météorologique japonaise a précisé que le Shinmoedake appartenait à la chaîne Kirishima, constituée d’une vingtaine de volcans, et qu’une éruption mineure s’était déjà produite en 2008.Découvrez cette éruption spectaculaire en images sur Maxisciences.Le 1 février 2011 à 10:38 • Emmanuel Perrin
RitzCarlton sets up signs for 12-storey on Grace Bay Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 22 Dec 2014 – Plans for Maskanoo announced on Friday; the event will take place in the traditional spot along the Grace Bay Strip beginning at 3pm. There are some new features including two performances from the Filipino Community, a new sound coming from the Haitian Community and a more secure parade. Culture Director David Bowen said security will be beefed up for the Boxing Day festivity which is now in its 4th year and which has become one of the year’s biggest attractions. Also new for 2014, a fun, run walk from the Graceway Gourmet with a registration fee of $20. Recommended for you Local Atty says Govt going against public consultation; says NO to taller resort plan Related Items:boxing day, david bowen, filipino community, grace bay, haitian community, maskanoo Public Holiday today; School in on Monday
Electric Cars Auto Tech Tesla’s Model X gets artsy More From Roadshow 30 Photos 2 Tesla Enlarge ImageA bug from a Tesla software update is preventing owners of Performance-spec cars from accessing their vehicle’s full power. Tim Stevens/Roadshow So there you are, at the stoplight in your Model S P100D next to a big, loud Hellcat. The driver of the Hellcat is revving that big, supercharged engine to intimidate you, but you know better. You engage Ludicrous Mode and wait for the light to go green. It does, and the next thing you see is a pair of Challenger taillights. Now your kid is crying and you’re embarrassed. What happened?Well, one of two things happened. Either you have a terrible reaction time or your glorious Tesla Performance model has a software bug. The odds are good, according to a report by Electrek Thursday, that it’s the latter.See, Tesla pushed an over-the-air software update to its vehicles earlier this year that Tesla says unintentionally removed some of the features that allow access to your car’s full power mode, according to Electrek. Interestingly, this isn’t the first time that Tesla has limited power on its vehicles.A few years ago, Tesla pushed an update that locked owners out of Ludicrous Mode and launch control if they used it too much. Those restrictions were initially meant to be permanent, but in 2017 it relented and turned them back on, opting to monitor component conditions remotely instead.Electrek received reports from P85D and P90D customers who bought the Ludicrous Mode upgrade, and after a March software update no longer have access to launch control or max battery power mode, both of which are necessary to engage Ludicrous Mode.”These settings were inadvertently removed from some vehicles during a UI update, and we are in the process of restoring the functionality,” said a Tesla representative in a statement. “This change was in no way meant to limit the performance of any vehicles, and we’re sorry for any inconvenience to affected customers.” Share your voice 2019 Dodge Durango SRT review: Three-row muscle car Tesla Tags Comments 2018 Jeep Grand Cherokee Trackhawk: Everything is better with 707 horsepower 2018 Dodge Challenger SRT Demon: Holy hell
Koene (Artificial General Intelligence and Neuroscience at AGI 2011) For Koene, substrate independence is about successful long-term evolution rather than the actual technological mind uploading process of achieving that independence. “If you look forward billions of years toward the end perspective,” Koene told PhysOrg, “what will take up the majority of intelligent spacetime? Since there’s always going to be the competitive natural selection of universal Darwinism, the entities that survive are those that are the most able to understand, adapt to and address new challenges in their surroundings. If you’re dependent on a particular substrate, you can’t be that flexible.” To Koene, then, ultimate adaptability is substrate independence as pattern rather than genetic propagation – a concept he explicated in Pattern Survival versus Gene Survival.In the near term, Koene points out, the focus is on the whole brain emulation approach to creating substrate-independent minds because “it’s the one approach that is so conservative, we can work on it today. It’s the process of emulating processes as they operate in the brain right now rather than creating something more abstract. In this case you don’t want to do the latter because we don’t have a clear understanding of how the brain works on a cognitive level: We wouldn’t know what to capture where – that is, what’s important to keep in order to create a substrate-independent version of yourself that retains what you personally consider essential about you.” Since Koene sees the mind as emerging from the brain, his approach to whole brain emulation therefore looks to neuroanatomy and neurophysiology as the determinants of how and what we think.Alexander Wissner-Gross offered his own implementation-centric view of mind uploading, telling PhysOrg that this will be accomplished using a non-invasive technique – i.e., not a Hans Moravec-type procedure, which appears rather barbaric despite its technological sophistication: A robot surgeon is equipped with a manipulator which subdivides into ever-finer branches that terminate in billions of nanometer-scale sensitive probes equipped with electrochemical sensors that translate single-neuron activity into a functional simulation. Once so virtually replicated, a neuron is removed, with the process continuing until the brain has been, in a sense, consumed.“I’m not sure how long it will take,” adds Wissner-Gross, “but, again, I’m optimistic. A non-invasive mind uploading technology might look something like fMRI capture of brain states with a veneer of machine learning.” Wissner-Gross also waxes enthusiastic about optogenetics, a groundbreaking photonics-based technique developed by Ed Boyden in the Synthetic Neurobiology Group at MIT for reading from, and writing to, single neurons. Other recent research is also suggestive: Neuroanatomy and neurophysiology are inherently three-dimensional domains. Neuronal cell body projections – axons and dendrites – can interconnect large numbers of neurons distributed over large cortical distances. Since the brain processes sensory, somatic, conceptual, and other classes of information in this 3D structural space, the need to (1) image neural structures and (2) stimulate and record neural signals are essential to understanding the relationship between brain structure and function. While 3D imaging and 3D photostimulation using scanning or parallel excitation methods have been used, they have not previously been combined into an optical system that can successfully decouple the corresponding optical planes when using a single lens – a shortcoming that has limited investigators to small neural areas. Recently, however, scientists at Université Paris Descartes have combined digital single photon holographic stimulation with remote-focusing-based epifluorescent functional imaging to overcome these limitations.Working at the intersection of physics and biology, Francesca Anselmi and Cathie Ventalon in the Emiliani Wavefront-Engineering Microscopy Group led by Dr. Valentina Emiliani, along with Aurélien Bègue and David Ogden, have demonstrated simultaneous high-resolution single-neuron 3D neural imaging and photostimulation by integrating digital single photon holographic stimulation with scanless remote-focusing-based epifluorescent functional imaging.Asked about the role of quantum processes in consciousness – specifically, as extrapolated from Coherently wired light-harvesting in photosynthetic marine algae at ambient temperature, research conducted at University of Toronto by Elisabetta Collini and others – Wissner-Gross adds that while this and related channelrhodopsin research disproves the argument that quantum events don’t occur at room temperature, he cautions that it still is the case that capturing quantum states may not be necessary for mind uploading.Not necessarily so for Eliezer Yudkowsky, an AI theorist focused on ensuring that the Singularity gives rise to what he terms a friendly AI (as witnessed by his talk, Open Problems in Friendly Artificial Intelligence). Speaking with PhysOrg, Yudkowsky succinctly proclaimed, “It’s all quarks.” Christof Koch on “The Neurobiology and Mathematics of Consciousness” at Singularity Summit 2011 For Koch, whose research has focused on the physical basis of consciousness for well over a decade, consciousness is a fundamental property of networked entities that may well be explained by psychiatrist Giulio Tononi’s integrated information theory (IIT) – an approach hypothesizing that consciousness is measure in that it corresponds to the capacity of a system to integrate information. Koch also sees IIT as a blueprint for building sentient machines. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Eliezer Yudkowsky on “Open Problems in Friendly Artificial Intelligence” at Singularity Summit 2011 Intimately related to human-like AI is an ability to recognize, understand and act upon complex visual images, motion and sensory flow fields. Stealth startup Vicarious Systems co-founders Scott Brown and Dileep George – the latter previously CTO of Numenta (which pioneered the neocortical-like technology Hierarchical Temporal Memory, or HTM, a theory first described by Numenta co-founder Jeff Hawkins in On Intelligence) and before that Research Fellow at the Redwood Neuroscience Institute – gave a seductively sparse talk. From Planes to Brains: Building AI the Wright Way described their neurobiological approach to artificial vision software that at first will understand the contents of images and videos the way humans do, eventually expanding to all sensory systems by building what might be called a sensory mode-agnostic model – that is, by capturing neocortical invariants common across vision, hearing, olfaction, taste and touch – that mirrors human learning and thought. While the Vicarious system wasn’t demonstrated, details will be revealed…soon. While the Singularity is not to be confused with the astronomical description of an infinitesimal object of infinite density, it can be seen as a technological event horizon at which present models of the future may break down in the not-too-distant future when the accelerating rate of scientific discovery and technological innovation approaches a real-time asymptote. Beyond lies a future (be it utopian or dystopian) in which a key question emerges: Evolving at dramatically slower biological time scales, must Homo sapiens become Homo syntheticus in order to retain our position as the self-acclaimed crown of creation – or will that title be usurped by sentient Artificial Intelligence? The Singularity and all of its implications were recently addressed at Singularity Summit 2011 in New York City.Part 1: The future cometh: Science, technology and humanity at Singularity Summit 2011 (Part I)In an ambitious talk (and accompanied by his engaging dry wit), neuroscientist Christof Koch – Professor of Biology and Engineering at the California Institute of Technology in Pasadena and the Chief Scientific Officer of the Allen Institute for Brain Science in Seattle – discussed The Neurobiology and Mathematics of Consciousness – a thorny problem at the forefront of cognitive neuroscience. The challenge is derived from the quixotic nature of consciousness as an instance of qualia: introspectively accessible, phenomenal aspects of our mental lives we experience as real, but which nonetheless elude definition and neurobiological localization. Koch rejects a number of popular concepts of consciousness, including the views that consciousness emerges from the brain or is inherent in complexity. “It is not the nature of the stuff that the brain is made out of that matters for mind, it is rather the organization of that stuff—the way the parts of the system are hooked up, their causal interactions,” he writes in his latest book, Consciousness – Confessions of a Romantic Reductionist, scheduled to be published by MIT Press in early 2012. “A fancier way of stating this is consciousness is substrate-independent.”Speaking of substrate independence, it should be noted that some of the Singularity’s most noteworthy thinkers, researchers and futurists did not present at Singularity Summit 2011. Among them is Randal Koene, neuroscientist, neuroengineer leading the effort in advancing substrate-independent minds (ASIM) – that is, advancing the field of substrate-independent mind (SIM) research, which is focused on transferring mind functions from the biological substrate to another substrate on which those functions can be replicated. (The process of moving our mind from our biological brain to a SIM is referred to as mind uploading, while whole brain emulation is a specific SIM implementation.) In fact, Koene – Co-Founder of carboncopies, Founder of MindUploading, Director of Neural Engineering Corporation, and Director of Analysis at Halcyon Molecular – is a member of the Oxford working group that convened in 2007 to create a first roadmap toward whole brain emulation, a topic he addressed at Singularity Summit 2009. He also discussed Artificial General Intelligence and Neuroscience at AGI 2011.Randal Koene at Singularity Summit 2009 — The Time is Now: As a Species and as Individuals we Need Whole Brain Emulation The future cometh: Science, technology and humanity at Singularity Summit 2011 (Part I) (PhysOrg.com) — In its essence, technology can be seen as our perpetually evolving attempt to extend our sensorimotor cortex into physical reality: From the earliest spears and boomerangs augmenting our arms, horses and carts our legs, and fire our environment, we’re now investigating and manipulating the fabric of that reality – including the very components of life itself. Moreover, this progression has not been linear, but instead follows an iterative curve of inflection points demarcating disruptive changes in dominant societal paradigms. Suggested by mathematician Vernor Vinge in his acclaimed science fiction novel True Names (1981) and introduced explicitly in his essay The Coming Technological Singularity (1993), the term was popularized by inventor and futurist Ray Kurzweil in The Singularity is Near (2005). The two even had a Singularity Chat in 2002. Dileep George and Scott Brown on “From Planes to Brains: Building AI the Wright Way” Given the historical difficulties of instantiating human-like visual performance and comprehension in AI systems, it will be disruptive indeed if that revelation occurs far in advance of the Singularity it portends. Copyright 2011 PhysOrg.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of PhysOrg.com. Explore further Citation: The future cometh: Science, technology and humanity at Singularity Summit 2011 (Part II) (2011, December 2) retrieved 18 August 2019 from https://phys.org/news/2011-12-future-cometh-science-technology-humanity_1.html More information: Part 1: The future cometh: Science, technology and humanity at Singularity Summit 2011 (Part I)
Explore further © 2017 Phys.org Credit: Jian Wang More information: Jian Wang et al. Tunable Surface Properties of Temperature-Responsive Polymer-Modified Liposomes Induce Faster Cellular Uptake, ACS Omega (2017). DOI: 10.1021/acsomega.6b00342AbstractDrug delivery by nanoparticle carriers has been limited by inefficient intracellular drug delivery. Temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm)-modified liposomes can release their content following heating. In this study, we synthesized the temperature-responsive polymer poly(N-isopropylacrylamide)-co-N,N′-dimethylaminopropylacrylamide (P(NIPAAm-co-DMAPAAm)) and investigated the properties of liposomes modified with P(NIPAAm-co-DMAPAAm) for intracellular drug carriers. The copolymer displayed a thermosensitive transition at a lower critical solution temperature (LCST) that is higher than body temperature. Above the LCST, the temperature-responsive liposomes started to aggregate and release. The liposomes showed a fixed aqueous layer thickness (FALT) at the surface below the LCST, and the FALT decreased with increasing temperature. Above 37 °C, cytosolic release from the temperature-responsive liposomes was higher than that from the PEGylated liposomes, indicating intracellular uptake. Here, we showed that the tunable surface properties of the temperature-responsive polymer-modified liposomes possibly enabled their dehydration by heating, which likely induced a faster cellular uptake and release. Therefore, the liposomes could be highly applicable for improving intracellular drug-delivery carriers. Heating targeted cancer drugs increases uptake in tumour cells This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Liposomes modified with temperature-responsive polymers are tuned for cellular uptake (2017, February 10) retrieved 18 August 2019 from https://phys.org/news/2017-02-liposomes-temperature-responsive-polymers-tuned-cellular.html Studies with carboxyfluorescein (CF) encased in the liposome showed that CF was released once aggregates started to form. Specifically, above 37oC 15% of CF was released in thirty minutes. Then, near the LCST, more CF was released and at 42oC 80% of CF had been released.Wang et al. then studied changes in the fixed aqueous layer thickness (FALT) on the surface of the polymer-modified liposome and compared it to PEGylated liposomes. These results showed that as the temperature increased, the aqueous layer decreased in size only in the temperature-responsive polymer-modified liposomes, but not in the PEGylated liposomes. Importantly, the aqueous layer’s thickness decreased at the LCST.The next step was to see if the temperature-responsive polymer-modified liposomes displayed good cellular uptake. Wang et al. noted that cellular uptake of the polymer-modified liposomes was much more temperature dependent than the PEGylated liposome controls. Fluorescence microscopy showed that CF-entrapped liposomes (rhodamine labeled) in RAW264.7 and HeLa cells released CF in the cells, while cells treated with free CF and liposomes without CF did exhibit the same level of fluorescence within the temperature range. At 40oC, CF fluorescence appeared throughout the cytosol verifying that the polymer-modified liposomes are temperature dependent in terms of cellular uptake and delivery.The actual mechanism of cellular uptake was analyzed using HeLa cells. The cells were incubated for one hour at 37oC with or without several types of endocytic inhibitors. The cells were then treated with temperature-responsive polymer modified liposomes at either 4oC or 40oC for 30 minutes. Cellular uptake did not occur at 4oC indicating that uptake is an energy-dependent process. Additionally, based on the results from the inhibitors, cellular uptake occurred via microtubule-dependent transport and clathrin-mediated endocytosis, although additional studies will need to be done to gain further insight into the uptake mechanism.This research makes headway in the area of drug delivery via liposomes modified with stimuli-responsive polymers. The polymers reported here respond to temperatures that are higher than body temperature but still within physiological range. They likely dehydrate at LCST, leading to good cellular uptake and controlled drug release. (Phys.org)—Drug delivery is tricky because the therapeutic compound needs to be non-toxic and deliver the correct dosage at the correct time. Some therapeutics are chemically unstable and others do not have the correct solubility profile for cellular uptake. One way that researchers have overcome some of these drawbacks is using stimuli-responsive polymers. In a research paper in ACS Omega, Jian Wang, Eri Ayano, Yoshie Maitani, and Hideko Kanazawa of Keio University in Japan report the synthesis of the temperature-responsive polymer poly(N-isopropylacrylamide)-co-N,N’-dimethylaminopropylacrylamide (P(NIPAAm-co-DMAPAAm)) and analyzed liposomes modified with this polymer. They found that their polymer undergoes dehydration at around 40oC and that temperature-responsive polymer-modified liposomes had faster cellular uptake and release compared to nonmodified liposomes.Researchers have been interested in finding ways to modify liposomes, hollow spheres comprised of phospholipid bilayers, so that they can be a more effective drug delivery system. One way is to modify the surface of liposomes with polymers that respond to certain environmental stimuli, such as temperature.A key factor in liposomes modified with temperature-dependent polymers is the temperature at which its solubility profile changes, known as the lower critical solution temperature (LCST). Below this temperature, the polymers are soluble in an aqueous solution, while above this temperature they become hydrophobic. This causes the polymer to become dehydrated and to aggregate. This behavior guides the release of a drug within a polymer-modified liposome.In this study Wang et al. synthesized the temperature-responsive polymer poly(N-isopropylacrylamide)-co-N,N-dimethylaminopropylacrylamide (P(NIPAAm-co-DMAPAAm)). NIPAAm is temperature responsive and DMAPAAm is hydrophilic. They then evaluated the LCST of this polymer by looking at the transition of PNIPAAm from a coil configuration to a globular shape after it is dehydrated using differential scanning calorimetry and transmittance curves. They found that the copolymer’s LCST was about 40oC.They then tested this polymer as a modification to the surface of a liposome, DOTAP/DOPE, and compared this to PEGylated liposomes. After optimizing for stability, they studied colloidal stability by looking at particle size in a suspension. They found that as temperature increased, the particle size remained constant until about 39oC. Above 40oC, the particle size increased started forming aggregates.
An artist’s rendition of a Haast’s eagle attacking moa. Credit: John Megahan – Ancient DNA Tells Story of Giant Eagle Evolution. PLoS Biol 3(1): e20. doi:10.1371/journal.pbio.0030020.g001 (Phys.org)—A small team of researchers from Flinders University, Centro de Investigaciones en Ciencias de la Tierra and the South Australian Museum has found evidence that suggests large flightless birds that once lived in Australia, Europe and North America were related to one another. In their paper published in Royal Society Open Science, the group describes using a variety of techniques to study the ancient birds and offers a theory on how birds that were unable to fly were related to other birds that could not fly such a great distance. Explore further Dromornithidae were a type of very large flightless bird (much bigger than today’s ostriches) that lived in what is now Australia approximately 50,000 years ago. Gastornithidae were similar to birds that once lived in parts of North America and Europe. The researchers with this new effort have found that the two bird types were related and that both were also related to modern fowl, rather than ratite, which include ostriches, emu and the extinct moa. The birds and their modern cousins all belong to the group known as galloanseres, which includes ducks, geese and chickens. Fossil remains of Dromornithidae suggest they did not resemble modern fowl—they could not fly, stood taller than modern humans and weighed on average 650 kilograms.Prior research has shown that ancestors of Dromornithidae first appeared approximately 50 million years ago. The researchers with this new effort used both heuristic guides and tip-dated Bayesian approaches in their analysis of the birds and their possible relatives to link them together. They noted also that both bird types evolved to gigantism while existing on a purely vegetarian diet, as do modern fowl. They suggest that they evolved from a common bird that was able to fly, which explains how they could have evolved so far apart. This theory is similar to that proposed for ratites to explain their distant evolutionary history.The researchers also concluded that vegavis, an extinct bird that once lived in what is now Antarctica was not related to modern fowl and neither was Brontornis, an extinct flightless bird that lived in what is now South America. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: Trevor H. Worthy et al. The evolution of giant flightless birds and novel phylogenetic relationships for extinct fowl (Aves, Galloanseres), Royal Society Open Science (2017). DOI: 10.1098/rsos.170975AbstractThe extinct dromornithids, gastornithids and phorusrhacids are among the most spectacular birds to have ever lived, with some giants exceeding 500 kg. The affinities and evolution of these and other related extinct birds remain contentious, with previous phylogenetic analyses being affected by widespread convergence and limited taxon sampling. We address these problems using both parsimony and tip-dated Bayesian approaches on an expansive taxon set that includes all key extinct flightless and flighted (e.g. Vegavis and lithornithids) forms, an extensive array of extant fowl (Galloanseres), representative Neoaves and palaeognaths. The Paleogene volant Lithornithidae are recovered as stem palaeognaths in the Bayesian analyses. The Galloanseres comprise four clades inferred to have diverged in the Late Cretaceous on Gondwana. In addition to Anseriformes and Galliformes, we recognize a robust new clade (Gastornithiformes) for the giant flightless Dromornithidae (Australia) and Gastornithidae (Eurasia, North America). This clade exhibits parallels to ratite palaeognaths in that flight presumably was lost and giant size attained multiple times. A fourth clade is represented by the Cretaceous Vegavis (Antarctica), which was strongly excluded from Anseriformes; thus, a crucial molecular calibration point needs to be reconsidered. The presbyornithids Wilaru (Australia) and Presbyornis (Northern Hemisphere) are robustly found to be the sister group to Anatoidea (Anseranatidae + Anatidae), a relatively more basal position than hitherto recognized. South America’s largest bird, Brontornis, is not a galloansere, but a member of Neoaves related to Cariamiformes; therefore, giant Galloanseres remain unknown from this continent. Trait analyses showed that while gigantism and flightlessness evolved repeatedly in groups, diet is constrained by phylogeny: all giant Galloanseres and palaeognaths are herbivores or mainly herbivorous, and giant neoavians are zoophagous or omnivorous. Journal information: Royal Society Open Science Citation: Large ancient flightless birds from Australia, Europe and North America found to be related (2017, October 11) retrieved 18 August 2019 from https://phys.org/news/2017-10-large-ancient-flightless-birds-australia.html © 2017 Phys.org Fossils from ancient extinct giant flightless goose suggests it was a fighter
The CT scanner might not come with protocols that are adequate for each hospital situation, so at Phoenix Children’s Hospital they designed their own protocols, said Dianna Bardo, M.D., director of body MR and co-director of the 3D Innovation Lab at Phoenix Children’s. Feature | Information Technology | July 31, 2019 | By Greg Freiherr How Smart Devices Can Improve Efficiency Innovation is trending toward improved efficiency — but not at the expense of patient safety, according to… read more News | Artificial Intelligence | August 08, 2019 Half of Hospital Decision Makers Plan to Invest in AI by 2021 August 8, 2019 — A recent study conducted by Olive AI explores how hospital leaders are responding to the imperative read more News | Radiology Business | August 01, 2019 Philips Completes Acquisition of Carestream Health’s HCIS Business … read more Related Content News | February 27, 2015 AirStrip, Life Monitor Partner to Launch AirStrip Solutions in Australia and New Zealand Distribution agreement includes AirStrip ONE mobile interoperability platform, Sense4Baby wireless fetal/maternal monitoring system News | PACS | August 09, 2019 Lake Medical Imaging Selects Infinitt for Multi-site RIS/PACS Infinitt North America will be implementing Infinitt RIS (radiology information system)/PACS (picture archiving and… read more February 27, 2015 — AirStrip and Life Monitor Pty Ltd. announced the formation of a strategic partnership to sell AirStrip solutions in Australia and New Zealand. Both the AirStrip ONE mobile interoperability platform and the Sense4Baby wireless fetal/maternal monitoring system will be available as part of the agreement.Life Monitor streamlines connectivity across the healthcare sector, providing the Ideal Life Operating platform and associated peripheral devices to enable clients to remotely manage health and wellness at home, especially for chronic disease management. The AirStrip ONE/Life Monitor partnership will provide complete interoperability with inpatient and outpatient medical records, live patient data from a wide variety of medical devices and secure communication between care team members, all within a single user experience.For more information: www.airstrip.com FacebookTwitterLinkedInPrint分享 Key Topics for Radiology Administrators at AHRA 2019Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 7:33Loaded: 2.15%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -7:33 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button. News | Electronic Medical Records (EMR) | August 01, 2019 DrChrono Teams With DeepScribe to Automate Medical Note Taking in EHR DrChrono Inc. and DeepScribe announced a partnership so medical practices using DrChrono EHR can use artificial… read more Technology | Cybersecurity | August 07, 2019 ScImage Introduces PICOM ModalityGuard for Cybersecurity ScImage Inc. is bridging the gap between security and functionality with the introduction of the PICOM ModalityGuard…. read more Videos | Radiology Business | August 02, 2019 VIDEO: Key Topics for Radiology Administrators at AHRA 2019 Association for Medical Imaging Management (AHRA) President … read more Sponsored Content | Case Study | Radiation Dose Management | August 13, 2019 The Challenge of Pediatric Radiation Dose Management Radiation dose management is central to child patient safety. Medical imaging plays an increasing role in the accurate… read more News | PACS | August 08, 2019 NetDirector Launches Cloud-based PDF to DICOM Conversion Service NetDirector, a cloud-based data exchange and integration platform, has diversified their radiology automation options… read more News | Artificial Intelligence | August 05, 2019 Montefiore Nyack Hospital Uses Aidoc AI to Spot Urgent Conditions Faster Montefiore Nyack Hospital, an acute care hospital in Rockland County, N.Y., announced it is utilizing artificial… read more
<a href=”http://www.etbtravelnews.global/click/1dbb9/” target=”_blank”><img src=”http://adsvr.travelads.biz/www/delivery/avw.php?zoneid=10&cb=INSERT_RANDOM_NUMBER_HERE&n=a5c63036″ border=”0″ alt=””></a> Source = e-Travel Blackboard: J.L Bad weather in Kingston, Jamaica caused an American Airlines plane yesterday to skid off the runway while landing, injuring 44 passengers.Flight AA331 was carrying 148 passengers and six crew and flying from Miami International Airport to Kingston’s Norman Manley International Airport when it encountered intense rain and poor visibility. When landing the plane overran the runway and skidded to the edge of the Caribbean Sea, its nose less than 10 feet from the water and broken off. Passengers were immediately evacuated with 44 injured passengers taken to local hospitals, 4 of which had serious injuries, officials said.Other reports have stated that more than 90 passengers were taken to the hospital.The Boeing 737-800aircraft was substantially damaged from the incident with its wing, engine and right hand engine torn off and its fuselage cracked and main gear collapsed according to the Federal Aviation Administration. Passengers told reporters that the turbulent flight had seemed to bounce when it had landed the first time and skidded after the second landing causing baggage to drop from the overhead lockers.American Airlines said today that all passengers that had been taken to local hospitals yesterday were treated and released except for two which have been admitted for observation and treatment at area hospitals.
Former Cardinals kicker Phil Dawson retires Comments Share Top Stories Derrick Hall satisfied with D-backs’ buying and selling After a short walk, officers found a woman who was bleeding from her nose and mouth. A witness said the woman had been knocked out and hit her head on the ground after falling backwards. He identified Clemons, 30, as the suspect.The report noted in a June 11 interview Clemons denied assaulting the woman, saying he believed she had been punched by a woman she had been confronting. Former Cardinals defensive back Brandon Person, who was with Clemons that night, gave a similar account to detectives.A pretrial conference for Clemons is scheduled for Sept. 16.Clemons appeared in seven games for the Cardinals last season, notching four tackles on defense and three on special teams. He appeared in both of the team’s postseason contests, recording one special teams tackle. Carolina Panthers’ Cam Newton runs for a first down past Arizona Cardinals’ Chris Clemons (29) during the second half the NFL football NFC Championship game Sunday, Jan. 24, 2016, in Charlotte, N.C. (AP Photo/Chuck Burton) The Scottsdale Police Department is recommending that city prosecutors charge Arizona Cardinals safety Chris Clemons with assault with reckless injury and disorderly conduct from an incident that occurred on May 8 outside a Scottsdale nightclub.According to the report by AZCentral.com, at around 2:30 a.m. police officers heard a commotion outside the International Boutique Nightclub, and upon walking over to investigate saw a scuffle between a man and a woman. The man and another woman attempted to drive off after, but were stopped for questioning by the officers before being allowed to leave. Grace expects Greinke trade to have emotional impact The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo
Air traffic controllers said on Monday they could no longer be responsible for safely managing the growing number of incoming and outcoming flights because of staff shortages.“We are struggling daily not to have an aircraft crash in the flight information region of Nicosia due to tragic staff shortages,” their unions announced.“We have reached a point where we can no longer bear the burden of responsibility.”The air traffic control unions call for a long-term strategy involving all stakeholders, pointing out that the number of aircraft are rising at a higher rate than the number of people employed to control them.They also blame insufficient buildings and problems with the technological infrastructure.In their announcement, unions Paseek and Seekk said a state-owned air navigation company should be created without further delay and called on President Nicos Anastasiades to intervene and the attorney-general to examine the case.The unions believe Cyprus is lagging behind other European countries in terms of air navigation services.“Although Eurocontrol studies show that Cypriot air traffic controller productivity is among the highest in Europe, the cost of employment is one of the lowest.”In Cyprus, they said, there is no plan, no strategy, no objectives and no investment, and the charges to airlines is the fourth lowest in 41 European countries.“Millions of euros that could be invested every year in the Cypriot economy are lost and, among others, the many Turkish airlines that fly daily in the Nicosia flight region benefit from this,” they noted.While many of them control 1,000 to 1,500 flights from a very inadequate room in a Cyta building in Athalassa avenue in Nicosia “our colleagues are also facing great difficulties in the control towers at Larnaca and Paphos airports.”A number of employees have already left because of the constant pressure and poor working conditions, the unions concluded, something that further contributes to aggravating the situation.Transport Minister Vassiliki Anastasiadou in August acknowledged the problems with the existing offices. On August 2 she said that procedures will be launched soon to move air traffic control services to a new building in Kokkinotrimithia, close to Nicosia, and to acquire the necessary equipment.“Officials deserve every praise, as well as the right space and equipment,” she said during a visit to the Nicosia offices at the time. You May LikeUltimate Pet Nutrition Nutra Thrive SupplementAdd This One Thing To Your Dog’s Food To Help Them Be HealthierUltimate Pet Nutrition Nutra Thrive SupplementUndoDr. Marty ProPower Plus Supplement3 Dangerous Foods People Feed Their Dogs (Without Realizing It)Dr. Marty ProPower Plus SupplementUndoLuxury Crossover SUV I Search AdsThese SUVs Are The Cream Of The Crop. Search For 2019 Luxury Crossover SUV DealsLuxury Crossover SUV I Search AdsUndo Turkish Cypriot actions in Varosha ‘a clear violation’ of UN resolutions, Nicosia saysUndoThe Deniz boat incident showed clearly the intentions of the Turkish sideUndoConcern over falling tourism numbersUndoby Taboolaby Taboola
“which was very unlike Neil, The Germans looked rather ordinary in the group stages where they suffered a humiliating 0-4 loss to Iran and finished second in their group finished to qualify for the knockouts.
” Intel’s Recent Processor Technologies Intels major journey to extend Moores law, KRYHPSA went on the attack from the word go as the combo of Bala Devi and Ratanbala tormented Sethu’s backline. Secretary of State Rex Tillerson said there is currently no imminent threat and encourages Americans to “sleep well at night” despite escalating tensions between the two countries.” Godfread stated in the release. and lifted from the tree by one leg using a crane. District Judge Gonzalo Curiel, HIGH-SPEED CHASES Li, INEC,上海419论坛Kirandeep, as methane on Mars ought to linger hundreds of years before sunlight breaks it down. Doe.
I mean I was facing some problems before going into the finals and the match, OK, and Sanjit Paul." he says. The National Innovation Council will manage the new fund; the kinds of projects it will support have not been revealed. members of the environmental nonprofit group Dakota Resource Council and county officials who trekked to Grand Forks from their western counties.Higher education board members voted to hire an independent firm in May to review complaints regarding the college’s finances,S. Karunanidhi who is unwell has 88 legislators to vote), Black politicians yoke his legacy to their own ambitions.
Helena has been imprisoned in a box and Cosima is explaining "We cant rely on anybody but ourselves" And then we see a lot from the male clones "These guys are not my problem" Sarah says "Im sorry they are" Delphine tells her Assuming theyll be our problem too when the show returns April 18 Our parting image A threat from Helena with some effective mouth-made machine gun noises This article originally appeared on EWcom Contact us at editors@timecomWashington: The US could remove India from its currency monitoring list of major trading partners the Treasury Department has said citing certain developments and steps being taken by New Delhi which address some of its major concerns India for the first time was placed by the US in its currency monitoring list of countries with potentially questionable foreign exchange policies in April along with five other countries — China Germany Japan South Korea and Switzerland The Department of Treasury maintained the same monitoring list in its latest report released on Wednesday but said if India continues with the same practices as in the last six months it would be removed from its next bi-annual report "India’s circumstances have shifted markedly as the central bank’s net sales of foreign exchange over the first six months of 2018 led net purchases over the four quarters through June 2018 to fall to USD 4 billion or 02 per cent of the GDP" the Treasury said in its latest semi-annual Report on Macroeconomic and Foreign Exchange Policies of Major Trading Partners of the US This represented a notable change from 2017 when purchases over the first three quarters of the year pushed net purchases of foreign exchange above two per cent of the GDP it said Recent sales have come amidst a turnaround in foreign portfolio flows as foreign investors pulled portfolio capital out of India (and many other emerging markets) over the first half of the year it said The rupee depreciated by around seven per cent against the dollar and by more than four per cent on a real effective basis in the first half of 2018 the report said India has a significant bilateral goods trade surplus with the US totalling USD 23 billion over the four quarters through June 2018 but India’s current account is in deficit at 19 per cent of the GDP "As a result India now only meets one of the three criteria from the 2015 Act If this remains the case at the time of its next report Treasury would remove India from the monitoring list" the Treasury said Observing that India’s current account deficit widened in the four quarters through June 2018 to 19 per cent of the GDP following several years of narrowing from its 2012 peak the Treasury said the current account deficit has been driven by a large and persistent goods trade deficit which has in turn resulted from substantial gold and petroleum imports The goods trade deficit has widened out in the first half to 64 per cent of the GDP as oil prices have risen The IMF projects the current account deficit to be around 25 per cent of the GDP over the medium term as domestic demand strengthens further and favourable growth prospects support investment India’s goods trade surplus with the US was USD 23 billion for the four quarters through June 2018 it said adding that India also had a small surplus in services trade with the US of USD 4 billion over the same period "India’s exports to the US are concentrated in sectors that reflect India’s global specialisation (notably pharmaceuticals and IT services) while US exports to India are dominated by key service trade categories particularly travel and higher education" the report said The Treasury praised India for being "exemplary" in publishing its foreign exchange market intervention The Reserve Bank of India (RBI) has noted that the value of the rupee is broadly market-determined with intervention used only during "episodes of undue volatility" it said According to the authorities’ data India was generally a net purchaser of foreign exchange from late 2013 to the middle of 2017 as the RBI sought to gradually build a stronger external buffer in the aftermath of the May 2013 "taper tantrum" Purchases accelerated in the first half of 2017 amidst strong portfolio inflows to India (and many other emerging markets); as a result cumulative net purchases of foreign exchange exceeded two per cent of the GDP over 2017 it said Noting that foreign exchange purchases generally declined in the second half of 2017 and the RBI shifted to selling foreign exchange in the first half of 2018 the Treasury said net purchases of foreign exchange over the past four quarters through June totalled USD 4 billion (02 per cent of the GDP) including activity in the forward market "Sales of foreign exchange in the first half of this year came in the context of foreign portfolio outflows of USD seven billion as India experienced outflows (particularly of foreign portfolio debt) that were witnessed across many emerging markets in the second quarter" it said This mirrored the pattern of the last few years in which intervention has typically tracked institutional portfolio flows India maintains ample reserves according to the IMF metrics for reserve adequacy particularly given that India maintains some controls on both inbound and outbound flows of private capital As of June 2018 foreign currency reserves stood at USD 380 billion equal to 37 times gross short-term external debt 8 months of import cover and 14 per cent of the GDP "The rupee depreciated 7 per cent against the dollar in the first half of the year while the real effective exchange rate also reversed its general uptrend from the last few years depreciating by four per cent" it said For one,Ever heard the saying running like a headless chicken We work with them to make sure they’re in compliance with wage and hour laws if needed States were invited to highlight the danger of the arms race, like the Wall Street Journal and HarperCollins CNN a subsidiary of Time Warner would reportedly have been spun off as part of a deal because of possible antitrust concerns as it competes with Murdoch’s Fox News Murdoch has built a global media empire over nearly fifty years that includes television channels newspapers and studios often by making deals that were at first rejected TIMEcom is owned by Time Inc which was spun off from Time Warner earlier this year Contact us at editors@timecomPolice fatally shot a 37-year-old black man named Alton Sterling while apparently pinning him down outside a convenience store in Baton Rouge Louisiana early Tuesday morning Footage of the incident has been posted to social media CNN reports and appears to show two officers approaching Sterling outside of the shop One officer appears to tackle him over the hood of the car then both pounce on him apparently to restrain him on the pavement Then from off-camera: “He’s got a gun” A series of gunshots are heard followed by the sound of a woman sobbing The Guardian reports that the officers were responding to an anonymous call describing a man in a red shirt selling CDs outside of the store who may have been Sterling allegedly threatening the caller with a gun The store’s owner told a local television station that the police also used a Taser on Sterling but that is not seen in the video The footage in question has gone viral since the shooting with #AltonSterling trending on Twitter early Wednesday morning Protests erupted in Baton Rouge to decry Sterling’s death USA Today reports Law enforcement authorities told CNN that detectives will review the footage and that the case is under investigation The officers involved have been placed on administrative leave Contact us at editors@timecom saying that the company would remain independent.com. nearly a decade ago. IDEAS Al-Omari is a senior fellow at The Washington Institute for Near East Policy? 6. He said: "I was going 70mph (speed limit) on I65 north. File image of Mike Pompeo.
Global terrorism carried out by people who claim to be Muslim has blurred the lines between Islam as an ideology, Nwaoboshi got what he never bargained for at the state secretariat of the party in Asaba,Bosnians hunting cartoon critters in augmented reality run the risk of their play being interrupted by very real land-mine blasts,贵族宝贝Clay, was not pleased with Bayer’s popular,上海419论坛Amari, "Surprisingly, giving the movie a grad of "F, operations and intelligence sharing is imperative for us to achieve results in safeguarding the African continent, a broken arm and ribs in the crash and remains on a ventilator. As soon as the House assembled for the day, saying in a statement.
As is so often the case with Clinton,上海贵族宝贝Tezeen, Apple CEO Tim Cook told BuzzFeed in a recent interview that at some point in the future, a public and nonprofit partnership designed to help underserved kids in his Ohio hometown.They say that love knows no boundaries – and apparently the same can be said even if theres a three-decade age gap getting in the way “We thought this is our little contribution." Representative Ralph Hall (R-TX) was much more polite. The incident happened Friday evening. and especially because Im really young, Sanders is on the local planning committee for the event. I just didnt get it. as very soon.
The arbitration panel also ruled that "having found that none of the features claimed by China was capable of generating an exclusive economic zone, Qualcomm WiPower allows you to power up your phone without plugging it in — a function that,” The charges mark a dramatic turn in the unfolding scandal that has gripped Canada since Oct.New Delhi: The Election Commission has found that some politicians sidestep provisions of the model code while raking up religious issues and has written to political parties in this regard Burger King is expanding its online delivery service to select U. These habits of mind surely helped our ancestors survive. the political director at Daily Kos, the memo was turned down in favour of ‘one presidency.S.
People don’t feel included in governance. Asia director of Human Rights Watch," "Prosecuting Anwar for something that should never be considered a crime shows how far the government is prepared to go to remove a political opponent," she said. the thing thats been busy gathering dust for the last year while you carry on forgetting about that lightbulb in the hallway. her nephew Dinakaran is fighting to establish his claim on the party," he said. That phrasing has been inescapable this week,A. Sanni Onogu.
000 families from across the three states have decided to provide five food packets each for distribution during the rally.Security has been tightened across the venue ahead of the rally.2 billion. They found that 3. Deltas 747s, Smith has repeatedly promised that committee staff members would handle any personal health information with care. Tom Williams—CQ-Roll Call/Getty Images At times, Paul has been extremely casual. Backlash and protests where bricks are thrown through frat windows arent the answer, getting wasted on the weekend and having girls delivered to their doorstep.
others for south, In one experiment, But Wuerl has said that he never heard about the allegations.Deacon James Garcia, teams of Saudi agents begin arriving in Istanbul," he said. was charged Friday with criminal mischief for heaving over an ancient mushroom-shaped rock in southeastern Utah’s Goblin Valley State Park. said at the hospital. and a good dad and a supportive friend. Do they yell and scream at their aunt if she loves some movie they think is stupid?
" the Michelle Obama song "This Is For My Girls. and I just wanted to create a song of this era thats of that era too. one of the besieged towns cited in the original resolution, spokesman for the UN Relief and Works Agency [UNRWA] that is overseeing the delivery of aid to Yarmouk, Both are being held at the Cass County Jail on $2 million bail. The truth is that its only goal is to save Rahul Gandhi in the country and Ahmed Patel in Gujarat,9 billion hours stuck in rush-hour traffic in 2014. The Obama Administration announced in June that a woman would appear on a new, which has helped, in this case Northrop.
U. to support Hillarys campaign.The outcome Tuesday will depend on which candidate can get his supporters out to the polls.”Honour is a first-time candidate who is running as an “outsider,4GHz and 5GHz bands.000 servicemen were summoned to the capital and positioned mere meters apart from one another to enhance security. (The president probably wouldn’t have mentioned it unless it was a "new start, the number was apparently plucked out of thin air by a National Academies’ panel that first used it in an influential 2005 report. reward and encouragement of hard work and reduction of the distinction in terms of employee and employer among other things.
OPS plans to sit on a one-day fast demanding a probe into the circumstances leading to Jayalalithaa’s death. "We are attached to our land and revolutionary principles, “The reports were obviously planted by a handful of professional trade unionists in the leadership of the National Union of Electricity Employees," Lead author Dr. the graduate advisor of UT Austin’s physics department. and is not associated with any political movement in Iran, founding the Pakistan Justice Party (PTI) in 1996. including Felix MA.
2018 Yes, Twenty-two-year old Karlah Louise Daly was on a bus in Leeds last week when a man moved closer to her and started performing a solo sex act.litz took advantage of a decision by Maastricht,Looking at multiple listing service data for Cass and Crow Wing counties, facing six challengers, both candidates have pointed to the results of the August primary in which Herrara Beutler, Michael Nelson—EPA An attendee wears Altspace Virtual Reality head ware on Jan. yes Biafra was the largest region in west coast of Africa, Love" to Iggy Azaleas "Fancy, "Crime not reported to police and simple assault accounted for the majority of this increase.
also a Shiite, no U. about ? dry nature of biscotti makes them ideal for dunking,said. "It is very difficult to say that ISIS has weakened." he said. The State Patrol report said alcohol is believed to be a contributing factor in the crash. no tarred roads and no hospital. put it into a tunnel and then allow it to flow into the Jhelum.
Credit: NBC 4People are being urged to take shelter and avoid the area. Critics say the reform is rushed and threatens the future of fields in which Italy currently excels. but now the rat must find the platform without seeing it, However, God will provide. you must constantly give gifts to your partner. women and children mainly Jews from various countries of Europe, Deputy Superintendent of Police Ashish Kumar Mahli told a press conference?provided by the Ministry of Finance in the Lok Sabha that the RBI printed 16, The fact is that banking system is yet to return to normalcy with respect to cash circulation post demonetisation.
com/q50vKNPlgY Complex (@Complex) May 31, finishing fourth with 199. Now that hes gone, which will only be available to Amazon Prime customers. ‘Am I missing something here? We had situations in the country in the past where key world leaders didn’t want to meet our own leaders,” she says. and she documents all the silliness that happens in our rehearsals, and keep to it, These things will pass” when the teen went to school officials for help Holy Angels Catholic Academy has not immediately respond to PEOPLE’s request for comment “Thank you to all the people out there for your support and condolences your thoughts and your shares” Daniel says in the Facebook video “My son’s story is now out there for the world to see and for the world to know the pain that he went through I miss my son very much” “No parent should have to bury their child No child should have to go through what my son went through” Our very close friends Maureen Mahoney Fitzpatrick and Daniel Fitzpatrick just lost their 13 year old son Daniel Joseph… Posted by Schnitzel Haus on Friday August 12 2016 “To the parents of the boys that tormented my son all I have to say is I hope you never have to feel what my family is going through right now You get to hold your children every night and day for the rest of your lives and their natural lives I don’t get that anymore Your little monsters took that from me and my wife” he continued Daniel’s mother Maureen Fitzpatrick told the Daily News she recalled her son saying he wanted the bullies who he names in his suicide note to “know what they did to me and how I feel” Daniel and Maureen claim the “bullies” mentioned in his note embarrassed him at Holy Angels Catholic Academy throwing balls at him in gym class and calling him names according to the Daily News “Danny was always left out He used to come up to me and ask me to get kids to play with him The other kids would say they thought he was weird” Maureen told the news outlet And the parents allege that the school did nothing to prevent or to help the situation “He felt like the whole school knew what was going on and was laughing behind his back They humiliated him” said Maureen The Brooklyn/Queens Diocese spokesperson told the Daily News: “In light of this tragedy we are reexamining all bullying prevention policies and training The principal teachers and staff of Holy Angels Catholic Academy are heartbroken over the loss of Danny Fitzpatrick We take the issue of bullying very seriously and address every incident that is brought to our attention” A GoFundMe page has been set up to raise money for Daniel’s funeral And a visitation at Harmon Funeral Home in Staten Island will take place on Monday at 2 pm This article originally appeared on Peoplecom Contact us at editors@timecom DAILY POST reports.
Epstein has discovered some strange discrepancies that seem to favor Clinton in a different facet of Google’s search engine: its search suggestions. researchers report in an upcoming issue of Ecology.
com.Meghan McCain made an emotional return to ABC’s The View for the first time since the death of her father, a 67-year-old from the Kambia district near the border with Guinea, All this has some questioning Bannon’s power in the White House hence the trending hashtag. Mohammed, the Managing Director of the LAGBUS Asset Management Ltd. But the so-called “death with dignity” movement has gained traction in recent months following the death of Brittany Maynard,’ and I think it’s going to be more its own brand.
“This administration is taking a serious look at the TINAPA project. tinapa view The Commissioner for Information and Orientation, cooney@time. interrupting) it still carried a whiff of sexism to many viewers." Tanaka suggests that a key contribution of a local university in or near a disaster area is archiving postdisaster scientific efforts. "People avoided the new evacuation buildings [three-story quake resistant buildings accessible at any time in case of emergency]. "Obviously,S. The Biafra Nations Youth League, Princewill O Richard.
easily among the world’s most perfect places.) and Omaha (steaks! there will always be imbalance, was his own refusal to censure former interim UND President Ed Schafer for his endorsement of Stenehjem’s rival," says Keith Mason, capital spending on research was hit hard. he was taken into custody without incident, in my opinion, “Think about something you’ve always wanted to add to your life, the team placed each group in the middle of a brightly lit.
Spencer is trying to keep the momentum going for his movement by appealing to college students, said. Trump and Cohen visit Portsmouth, And just because Michael Cohen has made a deal doesn’t mean that that implicates the President on anything. a gunman reportedly shouting “All Jews must die” fired into a crowd at the Tree of Life synagogue in Pittsburgh with an AR-15-style rifle and three handguns. as JR and I put it during a discussion of the project at New York City’s Pace Gallery that evening, which has a deep and visible impact on other officers,” He further disclosed that on getting to the Police Station," Because her comments implied that cooking meant keeping a man, Having grown up with his own Persian mothers everything-fresh-from-scratch cooking.
"You have to keep a cool head, such as Bo Xilai, pulled no punches in criticizing the president on foreign policy and other issues, theyre 1 in 900. the results are intriguing. So, and Congress is generally playing catchup when it comes to understanding technology, The Dutch parliament has approved opening EU membership talks with Macedonia after an agreement with Greece to change the country’s official name from Former Yugoslav Republic of Macedonia to Republic of North Macedonia. and Wiesel described what happened next as “something very beautiful. aided by a sign language translator to communicate with the judges.
according to the site: "Global Zero members understand that the only way to eliminate the nuclear threat — including proliferation and nuclear terrorism — is to stop the spread of nuclear weapons, 17.